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AP219

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Catalog No. T36240Cas No. 779282-36-9

AP39 is a compound used to increase hydrogen sulfide (H2S) levels within mitochondria; it consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219, as a control compound for AP39, contains the triphenylphosphonium scaffold but lacks the H2S-releasing portion.

AP219

AP219

😃Good
Catalog No. T36240Cas No. 779282-36-9
AP39 is a compound used to increase hydrogen sulfide (H2S) levels within mitochondria; it consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219, as a control compound for AP39, contains the triphenylphosphonium scaffold but lacks the H2S-releasing portion.
Pack SizePriceAvailabilityQuantity
1 mg$7835 days
5 mg$34835 days
10 mg$59535 days
25 mg$1,33035 days
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Product Introduction

Bioactivity
Description
AP39 is a compound used to increase hydrogen sulfide (H2S) levels within mitochondria; it consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219, as a control compound for AP39, contains the triphenylphosphonium scaffold but lacks the H2S-releasing portion.
Chemical Properties
Molecular Weight433.551
FormulaC28H34O2P
Cas No.779282-36-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 15 mg/mL
DMF: 10 mg/mL
PBS (pH 7.2): 1 mg/mL
DMSO: 20 mg/mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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