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Ara-F-NAD+

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Catalog No. T38730Cas No. 133575-27-6

Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.

Ara-F-NAD+

Ara-F-NAD+

😃Good
Catalog No. T38730Cas No. 133575-27-6
Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.
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Product Introduction

Bioactivity
Description
Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.
In vitro
The leucoyte surface antigen CD38 has been shown to be an ecto-enzyme with multiple catalytic activities. It is principally a NAD + glycohydrolase that transforms NAD + into ADP-ribose and nicotinamide. CD38 is also able to produce small amounts of cyclic ADP-ribose (ADP-ribosyl cyclase activity) and to hydrolyse this cyclic metabolite into ADP-ribose (cyclic ADP-ribose hydrolase activity)[1].
Chemical Properties
Molecular Weight665.421
FormulaC21H26FN7O13P2
Cas No.133575-27-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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