Shopping Cart

Remove All

Your shopping cart is currently empty

ATP synthase inhibitor 2

Resource Download

ATP synthase inhibitor 2

Catalog No. T61649Cas No. 2814540-76-4

ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1].

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
25 mg	$766	10-14 weeks
50 mg	$996	10-14 weeks
100 mg	$1,490	10-14 weeks

Bulk & Custom

Add to Cart

Questions

Product Introduction

Bioactivity

Description

In vitro

Treatment with ATP synthase inhibitor 2 (Compound 22) at concentrations ranging from 0 to 256 μg/mL for 12-15 hours inhibits ATP synthase activity without exhibiting broad-spectrum antibiotic effects against Pseudomonas aeruginosa. In cell viability assays conducted on MSSA and WTPA cell lines under similar conditions, Compound 22 demonstrated no antibacterial activity, with minimum inhibitory concentrations (MICs) exceeding 128 μg/mL for MSSA and 256 μg/mL for WTPA, respectively.

Chemical Properties

Molecular Weight	382.48
Formula	C21H22N2O3S
Cas No.	2814540-76-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc