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ATP synthase inhibitor 2
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Catalog No. T61649Cas No. 2814540-76-4
ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1].
ATP synthase inhibitor 2
😃Good
Catalog No. T61649Cas No. 2814540-76-4
ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $766 | 10-14 weeks | |
| 50 mg | $996 | 10-14 weeks | |
| 100 mg | $1,490 | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1]. |
| In vitro | Treatment with ATP synthase inhibitor 2 (Compound 22) at concentrations ranging from 0 to 256 μg/mL for 12-15 hours inhibits ATP synthase activity without exhibiting broad-spectrum antibiotic effects against Pseudomonas aeruginosa. In cell viability assays conducted on MSSA and WTPA cell lines under similar conditions, Compound 22 demonstrated no antibacterial activity, with minimum inhibitory concentrations (MICs) exceeding 128 μg/mL for MSSA and 256 μg/mL for WTPA, respectively. |
| Molecular Weight | 382.48 |
| Formula | C21H22N2O3S |
| Cas No. | 2814540-76-4 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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