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ATR-IN-6

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Catalog No. T63555Cas No. 2746446-99-9

ATR-IN-6 is a potent inhibitor of ATR, a protein kinase involved in genome stability and DNA damage repair and a member of the PIKK family. ATR-IN-6 has shown potential for ATR kinase-mediated diseases, such as proliferative diseases and cancer.

ATR-IN-6

ATR-IN-6

😃Good
Catalog No. T63555Cas No. 2746446-99-9
ATR-IN-6 is a potent inhibitor of ATR, a protein kinase involved in genome stability and DNA damage repair and a member of the PIKK family. ATR-IN-6 has shown potential for ATR kinase-mediated diseases, such as proliferative diseases and cancer.
Pack SizePriceAvailabilityQuantity
25 mg$1,5208-10 weeks
50 mg$1,9808-10 weeks
100 mg$2,5008-10 weeks
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Product Introduction

Bioactivity
Description
ATR-IN-6 is a potent inhibitor of ATR, a protein kinase involved in genome stability and DNA damage repair and a member of the PIKK family. ATR-IN-6 has shown potential for ATR kinase-mediated diseases, such as proliferative diseases and cancer.
Chemical Properties
Molecular Weight513.57
FormulaC28H28FN7O2
Cas No.2746446-99-9
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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