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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $3,020 | 10-14 weeks | |
50 mg | $3,980 | 10-14 weeks | |
100 mg | $5,500 | 10-14 weeks |
Description | Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase). |
In vitro | Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01?nM for both Aurora A and Aurora B kinase. |
In vivo | In vivo efficacy in a mouse xenograft tumor model when dosed orally, Aurora inhibitor 1 exhibits good drug exposure levels across species upon oral dosing and shows excellent. |
Molecular Weight | 459.57 |
Formula | C23H25N9S |
Cas No. | 2227019-45-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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