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Axitinib sulfoxide

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Catalog No. T21129Cas No. 1347304-18-0
Alias PF-03482595, Axitinib metabolite M12, AG-028458

Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.

Axitinib sulfoxide

Axitinib sulfoxide

😃Good
Catalog No. T21129Alias PF-03482595, Axitinib metabolite M12, AG-028458Cas No. 1347304-18-0
Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.
Pack SizePriceAvailabilityQuantity
1 mg$15535 days
5 mg$52835 days
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Product Introduction

Bioactivity
Description
Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.
AliasPF-03482595, Axitinib metabolite M12, AG-028458
Chemical Properties
Molecular Weight402.47
FormulaC22H18N4O2S
Cas No.1347304-18-0
Relative Density.1.43 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Axitinib sulfoxideAG028458PF 03482595AG 028458PF03482595
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