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AZ2

Name: AZ2
Brand: TargetMol
SKU: T36309
Price: 228 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T36309Cas No. 2231760-33-9

Alias AZ2

AZ2, a potent PI3Kγ inhibitor (pIC50 value: 9.3), is primarily utilized in the investigation of inflammatory and immune diseases[1].

AZ2

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Catalog No. T36309Alias AZ2Cas No. 2231760-33-9

AZ2, a potent PI3Kγ inhibitor (pIC50 value: 9.3), is primarily utilized in the investigation of inflammatory and immune diseases[1].

Pack Size	Price	Availability
5 mg	$297	6-8 weeks
25 mg	$916	6-8 weeks
50 mg	$1,190	6-8 weeks
100 mg	$1,860	6-8 weeks
1 mL x 10 mM (in DMSO)	$296	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	AZ2, a potent PI3Kγ inhibitor (pIC50 value: 9.3), is primarily utilized in the investigation of inflammatory and immune diseases[1].
In vitro	AZ2, administered at concentrations ranging from 0.1 to 100 nM for 1 hour in SKOV-3 cells, demonstrates exceptional selectivity towards PI3Kγ. This is further evidenced by its action in cells exhibiting a constitutively activated PI3K/Akt pathway[1].
Alias	AZ2

Chemical Properties

Molecular Weight	369.48
Formula	C₂₀H₂₃N₃O₂S
Cas No.	2231760-33-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (135.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7065 mL	13.5325 mL	27.0651 mL	135.3253 mL
5 mM	0.5413 mL	2.7065 mL	5.4130 mL	27.0651 mL
10 mM	0.2707 mL	1.3533 mL	2.7065 mL	13.5325 mL
20 mM	0.1353 mL	0.6766 mL	1.3533 mL	6.7663 mL
50 mM	0.0541 mL	0.2707 mL	0.5413 mL	2.7065 mL
100 mM	0.0271 mL	0.1353 mL	0.2707 mL	1.3533 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AZ 2AZ-2