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Utatrectinib

Name: Utatrectinib
Brand: TargetMol
SKU: T71484
Rating: 4.5 (1 reviews)

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Catalog No. T71484Cas No. 1079274-94-4

Alias AZD-7451

Utatrectinib (AZD-7451) is a potent, orally active, and selective Trk inhibitor that effectively inhibits TrkC activation and associated tumorigenic behaviors.

Utatrectinib

😃Good

Catalog No. T71484Alias AZD-7451Cas No. 1079274-94-4

Utatrectinib (AZD-7451) is a potent, orally active, and selective Trk inhibitor that effectively inhibits TrkC activation and associated tumorigenic behaviors.

Pack Size	Price	Availability
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Utatrectinib (AZD-7451) is a potent, orally active, and selective Trk inhibitor that effectively inhibits TrkC activation and associated tumorigenic behaviors.
Alias	AZD-7451

Chemical Properties

Molecular Weight	382.39
Formula	C₁₈H₁₉FN₈O
Cas No.	1079274-94-4

Storage & Solubility Information

Storage

Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NS0011AZD 7451AZD7451UtatrectinibNS 0011S00109