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Azido-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Azido-C1-PEG3-C3-NH2 |
Molecular Weight | 246.31 |
Formula | C10H22N4O3 |
Cas No. | 1162336-72-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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