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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG12-alcohol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands linked together—one binds to an E3 ubiquitin ligase and the other to the target protein—leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Azido-PEG12-alcohol |
Molecular Weight | 615.718 |
Formula | C26H53N3O13 |
Cas No. | 1111239-69-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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