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Description | Azido-PEG24-acid is a PEG-based linker for PROTACs, crucial for joining two essential ligands and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together, one binding to an E3 ubiquitin ligase and the other to a target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 1172.35 |
Formula | C51H101N3O26 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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