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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG3-Ala-Boc, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand binds an E3 ubiquitin ligase, and the other binds the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1]. |
Molecular Weight | 362.38 |
Formula | C14H26N4O7 |
Cas No. | 2054345-68-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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