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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $32 | 5 days | |
5 mg | $48 | 5 days | |
10 mg | $70 | 5 days | |
25 mg | $113 | 5 days |
Description | Azido-PEG4-(CH2)3OH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker; one targets an E3 ubiquitin ligase, while the other binds to the target protein. These molecules leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 277.32 |
Formula | C11H23N3O5 |
Cas No. | 2028281-87-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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