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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG8-propargyl is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins [1]. |
Alias | Azido-PEG8-propargyl |
Molecular Weight | 433.502 |
Formula | C19H35N3O8 |
Cas No. | 1196733-06-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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