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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $195 | 2-4 weeks | |
5 mg | $483 | 2-4 weeks | |
10 mg | $692 | 2-4 weeks | |
25 mg | $1,080 | 2-4 weeks | |
50 mg | $1,490 | 2-4 weeks | |
100 mg | $1,970 | 2-4 weeks |
Description | Azido-PEG8-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Azido-PEG8-TFP ester |
Molecular Weight | 615.576 |
Formula | C25H37F4N3O10 |
Cas No. | 1818294-49-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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