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Azodicarbonamide is the first nucleocapsid inhibitor known to inhibit HIV-1 and various retroviruses by targeting the nucleocapsid CCHC domains. In a standard cellular antiviral assay, the compound inhibited HIV-1RF-induced CEM-SS cytopathy with an EC50 value of 38 µM.
Description | Azodicarbonamide is the first nucleocapsid inhibitor known to inhibit HIV-1 and various retroviruses by targeting the nucleocapsid CCHC domains. In a standard cellular antiviral assay, the compound inhibited HIV-1RF-induced CEM-SS cytopathy with an EC50 value of 38 µM. |
Targets&IC50 | HIV-1 (cell-based assay):38 μM(EC50) |
Alias | NSC 674447, HPH-116, ADA |
Molecular Weight | 116.08 |
Formula | C2H4N4O2 |
Cas No. | 123-77-3 |
Storage | Shipping with blue ice. |
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