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BBO-10203

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Catalog No. T203428Cas No. 2971769-60-3

BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, hindering the interaction of K-, H-, and N-Ras with PI3Kα. It inhibits pAKT with an IC50 of less than 0.1 pM in BT474 cells.

BBO-10203

BBO-10203

😃Good
Catalog No. T203428Cas No. 2971769-60-3
BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, hindering the interaction of K-, H-, and N-Ras with PI3Kα. It inhibits pAKT with an IC50 of less than 0.1 pM in BT474 cells.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, hindering the interaction of K-, H-, and N-Ras with PI3Kα. It inhibits pAKT with an IC50 of less than 0.1 pM in BT474 cells.
Chemical Properties
Molecular Weight640.7
FormulaC34H30F2N6O3S
Cas No.2971769-60-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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