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BCAT-IN-1 is an orally active and selective BCATm inhibitor and a potential BCAT2 modulator, used in studies of metabolic diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $235 | In Stock | |
25 mg | $1,530 | In Stock | |
50 mg | $1,990 | 1-2 weeks | |
100 mg | $2,980 | 1-2 weeks |
Description | BCAT-IN-1 is an orally active and selective BCATm inhibitor and a potential BCAT2 modulator, used in studies of metabolic diseases. |
In vitro | BCAT-IN-1 inhibits BCATm in human cells with pIC50 of 7.0. BCAT-IN-1 inhibited BCATm in mice with pIC50 of 5.9 in cell tests. [1] |
In vivo | BCAT-IN-1 (compound 8b) (30-300 mg/kg, orally) increased BCAAs levels in a concentration-dependent manner in a mouse model of PD. [1] |
Molecular Weight | 538.46 |
Formula | C25H24BrN5O2S |
Cas No. | 2581243-32-3 |
Smiles | O=C(NC1CCCC(N2C(=NC=3C=C(C=CC32)C(=O)NC)C4=NC=CC=C4)C1)C=5SC(Br)=CC5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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