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BChE-IN-17 (compound 6n) is a potent and selective inhibitor of butyrylcholinesterase (BChE), with half-maximal inhibitory concentrations (IC50s) of 10.5 nM for equine BChE (eqBChE) and 32.5 nM for human BChE (hBChE). It shows over 1000-fold greater selectivity for BChE compared to acetylcholinesterase (AChE), while exhibiting low neurotoxicity and moderate neuroprotective effects [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | BChE-IN-17 (compound 6n) is a potent and selective inhibitor of butyrylcholinesterase (BChE), with half-maximal inhibitory concentrations (IC50s) of 10.5 nM for equine BChE (eqBChE) and 32.5 nM for human BChE (hBChE). It shows over 1000-fold greater selectivity for BChE compared to acetylcholinesterase (AChE), while exhibiting low neurotoxicity and moderate neuroprotective effects [1]. |
Targets&IC50 | BCHE (human):32.5 nM, AChE:686.4 μM, eqBCHE:10.5 nM |
Molecular Weight | 535.47 |
Formula | C23H23BrN2O4S2 |
Cas No. | 2425632-57-9 |
Storage | Shipping with blue ice. |
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