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BCL6-IN-4

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Catalog No. T36484Cas No. 2253879-65-9
Alias BCL6-IN-4

BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].

BCL6-IN-4

BCL6-IN-4

😃Good
Catalog No. T36484Alias BCL6-IN-4Cas No. 2253879-65-9
BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].
Pack SizePriceAvailabilityQuantity
25 mg$1,9008-10 weeks
50 mg$2,4808-10 weeks
100 mg$3,7008-10 weeks
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Product Introduction

Bioactivity
Description
BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].
Targets&IC50
BCL6:97 nM (IC50)
In vitro
BCL6-IN-4 (compound 25b) inhibits the growth of OCI-Ly1 and OCI-Ly3 cell lines, with GI50 values of 2.8 μM and 4.2 μM, respectively[1].
AliasBCL6-IN-4
Chemical Properties
Molecular Weight503.04
FormulaC25H35ClN6O3
Cas No.2253879-65-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 73.33 mg/mL (145.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9879 mL9.9396 mL19.8791 mL99.3957 mL
5 mM0.3976 mL1.9879 mL3.9758 mL19.8791 mL
10 mM0.1988 mL0.9940 mL1.9879 mL9.9396 mL
20 mM0.0994 mL0.4970 mL0.9940 mL4.9698 mL
50 mM0.0398 mL0.1988 mL0.3976 mL1.9879 mL
100 mM0.0199 mL0.0994 mL0.1988 mL0.9940 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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