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Benzyl-PEG2-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Benzyl-PEG2-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by incorporating two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein [1]. |
Alias | Benzyl-PEG2-acid |
Molecular Weight | 224.25 |
Formula | C12H16O4 |
Cas No. | 91555-65-6 |
Relative Density. | 1.1360 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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