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Benzyl-PEG5-azide, a PEG-based linker for PROTACs, joins two essential ligands crucial for the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Benzyl-PEG5-azide, a PEG-based linker for PROTACs, joins two essential ligands crucial for the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize two distinct ligands linked together: one targets an E3 ubiquitin ligase and the other binds to the target protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 353.41 |
Formula | C17H27N3O5 |
Cas No. | 86770-72-1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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