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Benzyl-PEG5-NHBoc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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500 mg | Inquiry | Backorder |
Description | Benzyl-PEG5-NHBoc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Benzyl-PEG5-NHBoc |
Molecular Weight | 427.538 |
Formula | C22H37NO7 |
Cas No. | 2064292-55-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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