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Benzylthiouracil

Name: Benzylthiouracil
Brand: TargetMol
SKU: T60268
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60268Cas No. 6336-50-1

Alias 6-Benzyl-2-thiouracil

Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.

Benzylthiouracil

🥰Excellent

Catalog No. T60268Alias 6-Benzyl-2-thiouracilCas No. 6336-50-1

Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.

Pack Size	Price	Availability
10 mg	$32	In Stock
25 mg	$42	In Stock
50 mg	$66	In Stock
100 mg	$95	In Stock
200 mg	$137	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.
In vivo	In rats, Benzylthiouracil was observed to be ten times more potent than thiouracil and methylthiouracil in inhibiting the thyroid's ability to naturally collect iodine, but there was no significant difference in the duration of inhibition at the smallest effective dose. [1]
Alias	6-Benzyl-2-thiouracil

Chemical Properties

Molecular Weight	218.28
Formula	C₁₁H₁₀N₂OS
Cas No.	6336-50-1
Smiles	O=C1C=C(NC(=S)N1)CC=2C=CC=CC2

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 180.00 mg/mL (824.63 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5813 mL	22.9064 mL	45.8127 mL	229.0636 mL
5 mM	0.9163 mL	4.5813 mL	9.1625 mL	45.8127 mL
10 mM	0.4581 mL	2.2906 mL	4.5813 mL	22.9064 mL
20 mM	0.2291 mL	1.1453 mL	2.2906 mL	11.4532 mL
50 mM	0.0916 mL	0.4581 mL	0.9163 mL	4.5813 mL
100 mM	0.0458 mL	0.2291 mL	0.4581 mL	2.2906 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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