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Bevifimod

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Catalog No. T82893Cas No. 2223113-32-2
Alias PRTX-100

Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].

Bevifimod

Bevifimod

😃Good
Catalog No. T82893Alias PRTX-100Cas No. 2223113-32-2
Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].
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Product Introduction

Bioactivity
Description
Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].
In vitro
Bevifimod (PRTX-100; concentrations of 250, 25, and 2.5 ng/mL; 48-hour exposure) inhibits the phagocytosis of W632-conditioned platelets by human monocytes in peripheral blood mononuclear cells (PBMC) [1].
In vivo
Bevifimod (PRTX-100; 2.5-250 µg/kg; i.v.; biweekly over 4 weeks) normalizes platelet counts within 1-2 weeks with no mortality in mice [2].
AliasPRTX-100
Chemical Properties
Cas No.2223113-32-2
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Related Tags: buy Bevifimod | purchase Bevifimod | Bevifimod cost | order Bevifimod | Bevifimod in vivo | Bevifimod in vitro
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