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Biotin-PEG23-amine is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Biotin-PEG23-amine is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 1299.6 |
Formula | C58H114N4O25S |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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