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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis(m-PEG4)-N-OH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 413.5 |
Formula | C18H39NO9 |
Cas No. | 2182601-79-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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