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Bis-isopropyl-PEG1, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-isopropyl-PEG1, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two ligands connected by a linker—one for an E3 ubiquitin ligase and the other for the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Bis-isopropyl-PEG1 |
Molecular Weight | 146.23 |
Formula | C8H18O2 |
Cas No. | 3944-35-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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