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Bis-NH2-C1-PEG3

Catalog No. T18618Cas No. 4246-51-9
Alias PROTAC Linker 24

Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker used in synthesizing PROTACs, aiding in the targeted degradation of specific proteins [1].

Bis-NH2-C1-PEG3

Bis-NH2-C1-PEG3

Catalog No. T18618Alias PROTAC Linker 24Cas No. 4246-51-9
Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker used in synthesizing PROTACs, aiding in the targeted degradation of specific proteins [1].
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100 mgInquiry7-10 days
500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker used in synthesizing PROTACs, aiding in the targeted degradation of specific proteins [1].
In vitro
PROTACs consist of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase while the other targets the protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1].
AliasPROTAC Linker 24
Chemical Properties
Molecular Weight220.31
FormulaC10H24N2O3
Cas No.4246-51-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Bis-NH-2-C1-PEG3BisNH2C1PEG3Bis NH2 C1 PEG3Bis-NH2-C1-PEG3
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