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Bis-PEG1-acid is a PEG-based linker for PROTACs [PROteolysis TArgeting Chimeras] that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bis-PEG1-acid is a PEG-based linker for PROTACs [PROteolysis TArgeting Chimeras] that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two ligands linked together—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 162.14 |
Formula | C6H10O5 |
Cas No. | 5961-83-1 |
Relative Density. | 1.316 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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