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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-PEG17-acid, a PEG-based linker for PROTACs, joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands connected by a linker—one ligand for an E3 ubiquitin ligase and the other for the target protein—exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 866.98 |
Formula | C38H74O21 |
Cas No. | 2226897-74-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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