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Bis-PEG3-acid, a PEG-based linker for PROTACs, connects two essential ligands to form PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bis-PEG3-acid, a PEG-based linker for PROTACs, connects two essential ligands to form PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase and the other the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 250.25 |
Formula | C10H18O7 |
Cas No. | 96517-92-9 |
Relative Density. | 1.239 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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