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Bis-PEG3-sulfonic acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-PEG3-sulfonic acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins, comprising two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein[1]. |
Molecular Weight | 322.35 |
Formula | C8H18O9S2 |
Cas No. | 255831-16-4 |
Relative Density. | 1.487 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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