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Bis-PEG4-acid

Name: Bis-PEG4-acid
Brand: TargetMol
SKU: T14638
Price: 29 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T14638Cas No. 31127-85-2

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Bis-PEG4-acid

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Catalog No. T14638Cas No. 31127-85-2

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Pack Size	Price	Availability	Quantity
500 mg	$50	7-10 days

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Product Introduction

Bioactivity

Description

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Chemical Properties

Molecular Weight	294.3
Formula	C₁₂H₂₂O₈
Cas No.	31127-85-2
Relative Density.	1.219 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 300 mg/mL (1019.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3979 mL	16.9895 mL	33.9789 mL	169.8947 mL
5 mM	0.6796 mL	3.3979 mL	6.7958 mL	33.9789 mL
10 mM	0.3398 mL	1.6989 mL	3.3979 mL	16.9895 mL
20 mM	0.1699 mL	0.8495 mL	1.6989 mL	8.4947 mL
50 mM	0.0680 mL	0.3398 mL	0.6796 mL	3.3979 mL
100 mM	0.0340 mL	0.1699 mL	0.3398 mL	1.6989 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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