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Bis-Tos-PEG6 is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bis-Tos-PEG6 is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two different ligands linked together: one targets an E3 ubiquitin ligase and the other binds the target protein. They leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Molecular Weight | 590.7 |
Formula | C26H38O11S2 |
Cas No. | 42749-27-9 |
Relative Density. | 1.227 g/cm3 at 25℃ |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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