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BM-131246

Catalog No. T10561Cas No. 103787-97-9

BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.

BM-131246

BM-131246

Purity: 100%
Catalog No. T10561Cas No. 103787-97-9
BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.
Pack SizePriceAvailabilityQuantity
1 mg$7006-8 weeks
5 mg$1,8006-8 weeks
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Purity:100%
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Product Introduction

Bioactivity
Description
BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.
In vivo
After repeated oral doses, BM-131246 attains approximately proportional increases in plasma levels in ob/ob mice. The terminal half-life for BM-131246 is about 4 h[1], and it is quickly absorbed into the bloodstream.
Chemical Properties
Molecular Weight408.47
FormulaC22H20N2O4S
Cas No.103787-97-9
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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