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BMS-986339

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Catalog No. T73155Cas No. 2477873-64-4

BMS-986339 is an orally active, potent FXR agonist that engages His298 and ASN287 residues via H-bond formation. It is employed in research on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) due to its anti-fibrosis properties.

BMS-986339

BMS-986339

😃Good
Catalog No. T73155Cas No. 2477873-64-4
BMS-986339 is an orally active, potent FXR agonist that engages His298 and ASN287 residues via H-bond formation. It is employed in research on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) due to its anti-fibrosis properties.
Pack SizePriceAvailabilityQuantity
25 mg$2,27010-14 weeks
50 mg$2,98010-14 weeks
100 mg$4,00010-14 weeks
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Product Introduction

Bioactivity
Description
BMS-986339 is an orally active, potent FXR agonist that engages His298 and ASN287 residues via H-bond formation. It is employed in research on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) due to its anti-fibrosis properties.
Chemical Properties
Molecular Weight643.71
FormulaC35H41F4N3O4
Cas No.2477873-64-4
Storage & Solubility Information
StorageShipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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