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Boc-NH-PEG2-C2-NHS ester

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Catalog No. T14736Cas No. 2183440-73-3

Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-derived PROTAC linker used in the synthesis of PROTACs [1].

Boc-NH-PEG2-C2-NHS ester

Boc-NH-PEG2-C2-NHS ester

😃Good
Catalog No. T14736Cas No. 2183440-73-3
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-derived PROTAC linker used in the synthesis of PROTACs [1].
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500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-derived PROTAC linker used in the synthesis of PROTACs [1].
In vitro
PROTACs feature two ligands connected by a linker: one binds an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
Chemical Properties
Molecular Weight374.39
FormulaC16H26N2O8
Cas No.2183440-73-3
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Boc-NH-PEG2-C2-NHS esterBoc-NH-PEG-2-C2-NHS esterBocNHPEG2C2NHS esterBoc NH PEG2 C2 NHS esterAlkyl/ether
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