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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Boc-NH-PEG5-azide, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein, thereby harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 406.47 |
Formula | C17H34N4O7 |
Cas No. | 911209-07-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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