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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Boc-NH-PEG6-propargyl, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation, enabling selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands joined by a linker; one binds to an E3 ubiquitin ligase, and the other targets the specific protein. These compounds leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Molecular Weight | 419.51 |
Formula | C20H37NO8 |
Cas No. | 1262991-52-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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