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Br-C3-methyl ester

Catalog No. T40574Cas No. 4897-84-1
Alias Br-C3-methyl ester

Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.

Br-C3-methyl ester

Br-C3-methyl ester

Catalog No. T40574Alias Br-C3-methyl esterCas No. 4897-84-1
Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.
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500 mg$427-10 days
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Product Introduction

Bioactivity
Description
Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.
In vitro
PROTACs, composed of two distinct ligands connected by a linker—one binding to an E3 ubiquitin ligase and the other to the target protein—utilize the ubiquitin-proteasome system to selectively degrade target proteins[1].
AliasBr-C3-methyl ester
Chemical Properties
Molecular Weight181.03
FormulaC5H9BrO2
Cas No.4897-84-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Br-C-3-methyl esterBrC3methyl esterBr C3 methyl ester
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