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Brassinazole

Name: Brassinazole
Brand: TargetMol
SKU: T60929
Price: 99 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60929Cas No. 280129-83-1

Alias (2S,3R)-Brassinazole

Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and development.

Brassinazole

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Purity: 99.71%

Catalog No. T60929Alias (2S,3R)-BrassinazoleCas No. 280129-83-1

Pack Size	Price	Availability	Quantity
1 mg	$99	In Stock

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Purity:99.71%

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COA LCMS

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Product Introduction

Bioactivity

Description	Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and development.
In vitro	At concentrations of 0.5, 1, and 5 μM, Brassinazole induces marked malformation of seedlings, rendering them morphologically similar to BR-deficient mutants. Cress treated with Brassinazole exhibits dwarfism and altered leaf morphology, characterized by downward curling and a dark green color typical of Arabidopsis BR-deficient mutants. This dwarfism is reversed by the application of 10 nM brassinolide [1].
Alias	(2S,3R)-Brassinazole

Chemical Properties

Molecular Weight	327.81
Formula	C₁₈H₁₈ClN₃O
Cas No.	280129-83-1
Smiles	[C@H]([C@@](C)(O)C1=CC=CC=C1)(CC2=CC=C(Cl)C=C2)N3C=NC=N3

Storage & Solubility Information

Storage

store at low temperature | Shipping with blue ice.

Solubility Information

DMSO: 30 mg/mL (91.52 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0505 mL	15.2527 mL	30.5055 mL	152.5274 mL
5 mM	0.6101 mL	3.0505 mL	6.1011 mL	30.5055 mL
10 mM	0.3051 mL	1.5253 mL	3.0505 mL	15.2527 mL
20 mM	0.1525 mL	0.7626 mL	1.5253 mL	7.6264 mL
50 mM	0.0610 mL	0.3051 mL	0.6101 mL	3.0505 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc