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Bromo-PEG4-MS is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
Description | Bromo-PEG4-MS is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Bromo-PEG4-MS |
Molecular Weight | 335.21 |
Formula | C9H19BrO6S |
Cas No. | 2167807-41-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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