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Bromo-PEG6-bromide is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | 5 days | |
10 mg | $38 | 5 days | |
25 mg | $59 | 5 days | |
50 mg | $85 | 5 days | |
100 mg | $143 | 5 days |
Description | Bromo-PEG6-bromide is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [2]. |
Molecular Weight | 452.18 |
Formula | C14H28Br2O6 |
Cas No. | 72713-23-6 |
Relative Density. | 1.394 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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