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Bromodomain inhibitor-8

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Catalog No. T10621Cas No. 1300031-70-2

Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.

Bromodomain inhibitor-8

Bromodomain inhibitor-8

😃Good
Catalog No. T10621Cas No. 1300031-70-2
Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.
Pack SizePriceAvailabilityQuantity
5 mg$3476-8 weeks
25 mg$9876-8 weeks
50 mg$1,3606-8 weeks
100 mg$2,1906-8 weeks
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Product Introduction

Bioactivity
Description
Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.
Chemical Properties
Molecular Weight448.94
FormulaC26H25ClN2O3
Cas No.1300031-70-2
Relative Density.1.251 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (222.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2275 mL11.1373 mL22.2747 mL111.3735 mL
5 mM0.4455 mL2.2275 mL4.4549 mL22.2747 mL
10 mM0.2227 mL1.1137 mL2.2275 mL11.1373 mL
20 mM0.1114 mL0.5569 mL1.1137 mL5.5687 mL
50 mM0.0445 mL0.2227 mL0.4455 mL2.2275 mL
100 mM0.0223 mL0.1114 mL0.2227 mL1.1137 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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