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Bromodomain inhibitor-8

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Bromodomain inhibitor-8

Catalog No. T10621Cas No. 1300031-70-2

Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.

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Pack Size	Price	Availability
5 mg	$347	6-8 weeks
25 mg	$987	6-8 weeks
50 mg	$1,360	6-8 weeks
100 mg	$2,190	6-8 weeks

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Product Introduction

Bioactivity

Description

Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.

Chemical Properties

Molecular Weight	448.94
Formula	C26H25ClN2O3
Cas No.	1300031-70-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (222.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2275 mL	11.1373 mL	22.2747 mL	111.3735 mL
5 mM	0.4455 mL	2.2275 mL	4.4549 mL	22.2747 mL
10 mM	0.2227 mL	1.1137 mL	2.2275 mL	11.1373 mL
20 mM	0.1114 mL	0.5569 mL	1.1137 mL	5.5687 mL
50 mM	0.0445 mL	0.2227 mL	0.4455 mL	2.2275 mL
100 mM	0.0223 mL	0.1114 mL	0.2227 mL	1.1137 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Bromodomain inhibitor 8Bromodomain inhibitor-8Bromodomain inhibitor8