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c(phg-isoDGR- (NMe)k) TFA (1844830-65-4 free base)

c(phg-isoDGR-(NMe)k) TFA is a potent and selective α5β1-integrin ligand (IC50: 2.9 nM).

Catalog No. T13631L

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c(phg-isoDGR- (NMe)k) TFA (1844830-65-4 free base)

Catalog No. T13631L

c(phg-isoDGR-(NMe)k) TFA is a potent and selective α5β1-integrin ligand (IC50: 2.9 nM).

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$486	Backorder
5 mg	$864	Backorder
10 mg	$1,323	Backorder
50 mg	Inquiry	Backorder
100 mg	Inquiry	Backorder
1 mL x 10 mM (in DMSO)	$1,364	Backorder

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Product Introduction

Bioactivity

Description	c(phg-isoDGR-(NMe)k) TFA is a potent and selective α5β1-integrin ligand (IC50: 2.9 nM).
Targets&IC50	α5β1:2.9 nM
In vivo	c(phg-isoDGR-(NMe)k) is trimerized with the chelator TRAP and used as a positron-emission tomography tracer for monitoring α5β1 integrin expression in an M21 mouse xenograft
Alias	c(phg-isoDGR-(NMe)k) TFA

Chemical Properties

Molecular Weight	717.69
Formula	C₂₉H₄₂F₃N₉O₉
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (348.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3934 mL	6.9668 mL	13.9336 mL	69.6680 mL
5 mM	0.2787 mL	1.3934 mL	2.7867 mL	13.9336 mL
10 mM	0.1393 mL	0.6967 mL	1.3934 mL	6.9668 mL
20 mM	0.0697 mL	0.3483 mL	0.6967 mL	3.4834 mL
50 mM	0.0279 mL	0.1393 mL	0.2787 mL	1.3934 mL
100 mM	0.0139 mL	0.0697 mL	0.1393 mL	0.6967 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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