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cIAP1 ligand 1

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Purity:98.77%

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COA HNMR HPLC

cIAP1 ligand 1

Catalog No. T17870Cas No. 2095244-42-9

cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used in conjunction with androgen receptor ligands for the development of protein degradation agents that can be used in the study of prostate cancer.

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Pack Size	Price	Availability
1 mg	$48	In Stock
5 mg	$117	In Stock
10 mg	$169	In Stock
25 mg	$289	In Stock
50 mg	$455	In Stock
100 mg	$728	In Stock

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Product Introduction

Bioactivity

Description	cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used in conjunction with androgen receptor ligands for the development of protein degradation agents that can be used in the study of prostate cancer.
Alias	E3 ligase Ligand 12

Chemical Properties

Molecular Weight	598.75
Formula	C31H42N4O6S
Cas No.	2095244-42-9

Storage & Solubility Information

Storage

store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL (133.61 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6701 mL	8.3507 mL	16.7015 mL	83.5073 mL
5 mM	0.3340 mL	1.6701 mL	3.3403 mL	16.7015 mL
10 mM	0.1670 mL	0.8351 mL	1.6701 mL	8.3507 mL
20 mM	0.0835 mL	0.4175 mL	0.8351 mL	4.1754 mL
50 mM	0.0334 mL	0.1670 mL	0.3340 mL	1.6701 mL
100 mM	0.0167 mL	0.0835 mL	0.1670 mL	0.8351 mL

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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