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CA-170

Catalog No. T12378LCas No. 1673534-76-3

PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.

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Pack Size	Price	Availability
25 mg	$1,450	8-10 weeks
50 mg	$1,890	8-10 weeks
100 mg	$2,580	8-10 weeks

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Questions

Product Introduction

Bioactivity

Description	PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.
In vitro	PD-1 is a co-receptor that is expressed predominantly by T cells. The binding of PD-1 to its ligands, PD-L1 or PD-L2, is important for the physiological regulation of the immune system[1].
Alias	PD-1-IN-1

Chemical Properties

Molecular Weight	360.32
Formula	C12H20N6O7
Cas No.	1673534-76-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 28.5 mg/mL (79.10 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7753 mL	13.8766 mL	27.7531 mL	138.7655 mL
5 mM	0.5551 mL	2.7753 mL	5.5506 mL	27.7531 mL
10 mM	0.2775 mL	1.3877 mL	2.7753 mL	13.8766 mL
20 mM	0.1388 mL	0.6938 mL	1.3877 mL	6.9383 mL
50 mM	0.0555 mL	0.2775 mL	0.5551 mL	2.7753 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc