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Calcium-Sensing Receptor Antagonists I

Name: Calcium-Sensing Receptor Antagonists I
Brand: TargetMol
SKU: T10665
Rating: 4.5 (1 reviews)

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Catalog No. T10665Cas No. 478963-79-0

Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.

Calcium-Sensing Receptor Antagonists I

😃Good

Catalog No. T10665Cas No. 478963-79-0

Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.

Pack Size	Price	Availability
2 mg	$59	5 days
5 mg	$112	5 days
1 mL x 10 mM (in DMSO)	$178	5 days

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Product Introduction

Bioactivity

Description

Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.

Chemical Properties

Molecular Weight	360.45
Formula	C₂₃H₂₄N₂O₂
Cas No.	478963-79-0
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (277.43 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7743 mL	13.8715 mL	27.7431 mL	138.7155 mL
5 mM	0.5549 mL	2.7743 mL	5.5486 mL	27.7431 mL
10 mM	0.2774 mL	1.3872 mL	2.7743 mL	13.8715 mL
20 mM	0.1387 mL	0.6936 mL	1.3872 mL	6.9358 mL
50 mM	0.0555 mL	0.2774 mL	0.5549 mL	2.7743 mL
100 mM	0.0277 mL	0.1387 mL	0.2774 mL	1.3872 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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