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CAY10443

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Catalog No. T36190Cas No. 582314-48-5
Alias CAY10443

Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 μM. These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.

CAY10443

CAY10443

😃Good
Catalog No. T36190Alias CAY10443Cas No. 582314-48-5
Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 μM. These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.
Pack SizePriceAvailabilityQuantity
5 mg$12335 days
10 mg$23035 days
25 mg$54035 days
50 mg$96335 days
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Product Introduction

Bioactivity
Description
Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 μM. These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.
AliasCAY10443
Chemical Properties
Molecular Weight336.21
FormulaC17H15Cl2NO2
Cas No.582314-48-5
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL
DMF: 30 mg/mL
DMSO:PBS (pH 7.2)(1:2: 0.25 mg/mL
Ethanol: 5 mg/mL

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Keywords

CAY 10443CAY-10443
Related Tags: buy CAY10443 | purchase CAY10443 | CAY10443 cost | order CAY10443 | CAY10443 chemical structure | CAY10443 formula | CAY10443 molecular weight
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